GRAP2

This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Full Name
GRB2-Related Adaptor Protein 2
Function
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Biological Process
Cell-cell signaling Source: ProtInc
Ras protein signal transduction Source: ProtInc
Cellular Location
Endosome; Nucleus; Cytoplasm
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Anti-GRAP2 antibodies

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Mouse Anti-GRAP2 Recombinant Antibody (CBLG1-1697) (CBMAB-G4783-LY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLG1-1697
Application*: WB
Datasheet SDS

Mouse Anti-GRAP2 Recombinant Antibody (CBLG1-1694) (CBMAB-G4780-LY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBLG1-1694
Application*: E, IP, IF, WB
Datasheet SDS

Mouse Anti-GRAP2 Recombinant Antibody (CBLG1-1693) (CBMAB-G4779-LY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-1693
Application*: WB, IP, F
Datasheet SDS

Mouse Anti-GRAP2 Recombinant Antibody (40) (CBMAB-G4778-LY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 40
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-GRAP2 Recombinant Antibody (CBLG1-2939) (CBMAB-G4777-LY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLG1-2939
Application*: WB
Datasheet SDS

Mouse Anti-GRAP2 Recombinant Antibody (1G12) (CBMAB-G4774-LY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G12
Application*: E, WB, IP, P
Datasheet SDS

Mouse Anti-GRAP2 Recombinant Antibody (CBLG1-216) (CBMAB-G0752-LY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-216
Application*: WB, IP, F
Datasheet SDS

Mouse Anti-GRAP2 Recombinant Antibody (CBFYH-2984) (CBMAB-H1341-FY)

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Target: GRAP2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBFYH-2984
Application*: E, IP, IF, WB
Datasheet SDS

GRAP2 Matched Antibody Pair (497) (APMAB-497LY)

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Target: GRAP2
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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