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Mouse Anti-GRAP2 Recombinant Antibody (CBLG1-216) (CBMAB-G0752-LY)

This product is antibody recognizes GRAP2. The antibody CBLG1-216 immunoassay techniques such as: ELISA, IHC, WB.
See all GRAP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-216
Antibody Isotype
IgG2a
Application
ELISA, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.09% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GRB2-Related Adaptor Protein 2
Introduction
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Entrez Gene ID
9402
UniProt ID
O75791
Alternative Names
GRB2-Related Adaptor Protein 2; Hematopoietic Cell-Associated Adapter Protein GrpL; Growth Factor Receptor-Binding Protein; SH3-SH2-SH3 Adapter Mona; Grf40 Adapter Protein; Adapter Protein GRID; GRB-2-Like Protein; Grf-40; GRB2L; GRBLG; GrbX; GADS; GRID;
Function
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Biological Process
Cell-cell signaling Source: ProtInc
Ras protein signal transduction Source: ProtInc
Cellular Location
Endosome; Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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