Full length human recombinant protein of human HAND1 produced in E.coli
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Heart And Neural Crest Derivatives Expressed 1; Extraembryonic Tissues, Heart, Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 1; Class A Basic Helix-Loop-Helix Protein 27; BHLHa27; EHand; Heart- And Neural Crest Derivatives-Expressed Protein 1; Thing1; Hxt