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Mouse Anti-HBG1 (N-terminus) Recombinant Antibody (CBFYH-3538) (CBMAB-H4090-FY)

This product is mouse antibody that recognizes HBG1. The antibody CBFYH-3538 can be used for immunoassay techniques such as: ELISA, WB.
See all HBG1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-3538
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Synthetic peptide corresponding to amino acid residues near the N-terminus of HBG1 conjugated to KLH
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1.0 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
N-terminus

Target

Full Name
Hemoglobin Subunit Gamma 1
Introduction
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Entrez Gene ID
3047
UniProt ID
P69891
Alternative Names
Hemoglobin Subunit Gamma 1; Hemoglobin Gamma-1 Chain; Hemoglobin Gamma-A Chain; Hemoglobin, Gamma A; Gamma-1-Globin; Hb F Agamma; Hemoglobin, Gamma, Regulator Of; Hemoglobin Subunit Gamma-1; Gamma A Hemoglobin
Function
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Biological Process
Cellular oxidant detoxification Source: GOC
Hydrogen peroxide catabolic process Source: GO_Central
Cellular Location
Cytosol; Hemoglobin complex; Haptoglobin-hemoglobin complex
PTM
Acetylation of Gly-2 converts Hb F to the minor Hb F1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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