HBG1

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
Full Name
Hemoglobin Subunit Gamma 1
Function
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
Biological Process
Cellular oxidant detoxification Source: GOC
Hydrogen peroxide catabolic process Source: GO_Central
Cellular Location
Cytosol; Hemoglobin complex; Haptoglobin-hemoglobin complex
PTM
Acetylation of Gly-2 converts Hb F to the minor Hb F1.
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Anti-HBG1 antibodies

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Mouse Anti-HBG1 Recombinant Antibody (HBF-1) (CBMAB-F0510-CQ)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HBF-1
Application*: F
Datasheet SDS

Mouse Anti-HBG1 Recombinant Antibody (953) (CBMAB-AP2672LY)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 953
Application*: ELISA, IHC
Datasheet SDS

Mouse Anti-HBG1 Recombinant Antibody (CF195) (CBMAB-FT293LY)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF195
Application*: ELISA, IHC
Datasheet SDS

Mouse Anti-HBG1 Recombinant Antibody (1G8) (CBMAB-A3758-LY)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G8
Application*: SE, E
Datasheet SDS

Mouse Anti-HBG1 Recombinant Antibody (BRIC111) (CBMAB-C5022WJ)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BRIC111
Application*: IH
Datasheet SDS

Rabbit Anti-HBG1 Recombinant Antibody (CBXF-1267) (CBMAB-F1018-CQ)

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Target: HBG1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Human
Clone: CBXF-1267
Application*: WB
Datasheet SDS

Rabbit Anti-HBG1 Recombinant Antibody (CBXF-1268) (CBMAB-F1017-CQ)

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Target: HBG1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1268
Application*: WB
Datasheet SDS

Mouse Anti-HBG1 (N-terminus) Recombinant Antibody (CBFYH-3538) (CBMAB-H4090-FY)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-3538
Application*: E, WB
Datasheet SDS

Rabbit Anti-HBG1 Recombinant Antibody (CBFYH-0753) (CBMAB-H1657-FY)

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Target: HBG1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0753
Application*: WB, F
Datasheet SDS

Mouse Anti-HBG1 (AA 1-147) Recombinant Antibody (CBFYH-0752) (CBMAB-H1656-FY)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-0752
Application*: E
Datasheet SDS

Mouse Anti-HBG1 Recombinant Antibody (2A4B5) (CBMAB-H1655-FY)

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Target: HBG1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2A4B5
Application*: E, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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