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Mouse Anti-HCCS Recombinant Antibody (3C7) (CBMAB-A3764-LY)

The product is antibody recognizes HCCS. The antibody 3C7 immunoassay techniques such as: IP, ELISA.
See all HCCS antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3C7
Antibody Isotype
IgG2a, κ
Application
IP, ELISA

Basic Information

Immunogen
HCCS (AAH01691, 1 a.a. ~ 268 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
holocytochrome c synthase (cytochrome c heme-lyase)
Entrez Gene ID
3052
UniProt ID
P53701
Alternative Names
CCHL; DKFZp779I1858; MCOPS7
Function
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
Biological Process
Animal organ morphogenesis Source: ProtInc
Cytochrome c-heme linkage Source: UniProtKB
Cellular Location
Mitochondrion inner membrane; Membrane
Involvement in disease
Linear skin defects with multiple congenital anomalies 1 (LSDMCA1):
A disorder characterized by dermal, ocular, neurological and cardiac abnormalities. LSDMCA1 main features are unilateral or bilateral microphthalmia, linear skin defects in affected females, and in utero lethality for males. Skin defects are limited to the face and neck, consisting of areas of aplastic skin that heal with age to form hyperpigmented areas. Additional features in female patients include agenesis of the corpus callosum, sclerocornea, chorioretinal abnormalities, infantile seizures, congenital heart defect, mental retardation, and diaphragmatic hernia. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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