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Mouse Anti-HENMT1 (AA 36-135) Recombinant Antibody (CBFYH-3554) (CBMAB-H4107-FY)

This product is mouse antibody that recognizes HENMT1. The antibody CBFYH-3554 can be used for immunoassay techniques such as: ELISA, ICC, IF, WB.
See all HENMT1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-3554
Antibody Isotype
IgG2a, κ
Application
ELISA, ICC, IF, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 36-135

Target

Full Name
HEN Methyltransferase 1
Introduction
HENMT1 (HEN Methyltransferase 1) is a Protein Coding gene. Among its related pathways are Mitotic Prophase and Gene Expression. Gene Ontology (GO) annotations related to this gene include RNA binding and RNA methyltransferase activity.
Entrez Gene ID
113802
UniProt ID
Q5T8I9
Alternative Names
HEN Methyltransferase 1; HEN1 Methyltransferase Homolog 1; C1orf59; HEN1 Methyltransferase Homolog 1 (Arabidopsis); Hua Enhancer 1 Homolog 1 (Arabidopsis); Chromosome 1 Open Reading Frame 59
Function
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Biological Process
piRNA metabolic process Source: UniProtKB
Production of siRNA involved in RNA interference Source: GO_Central
RNA methylation Source: FlyBase
Cellular Location
Cytoplasm. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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