Mouse Anti-HLA-E Recombinant Antibody (A239) (CBMAB-AP9790LY)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Antibacterial humoral response Source: UniProtKB
Antigen processing and presentation of endogenous peptide antigen via MHC class Ib Source: UniProtKB
Antigen processing and presentation of exogenous peptide antigen via MHC class Ib Source: UniProtKB
Antigen processing and presentation of peptide antigen via MHC class I Source: UniProtKB-KW
CD8-positive, alpha-beta T cell activation Source: UniProtKB
Defense response to Gram-positive bacterium Source: UniProtKB
Innate immune response Source: UniProtKB-KW
Natural killer cell tolerance induction Source: UniProtKB
Negative regulation of natural killer cell mediated cytotoxicity Source: UniProtKB
Positive regulation of antibody-dependent cellular cytotoxicity Source: UniProtKB
Positive regulation of CD8-positive, alpha-beta T cell activation Source: UniProtKB
Positive regulation of CD8-positive, alpha-beta T cell proliferation Source: UniProtKB
Positive regulation of immunoglobulin production Source: UniProtKB
Positive regulation of interleukin-13 production Source: UniProtKB
Positive regulation of interleukin-4 production Source: UniProtKB
Positive regulation of natural killer cell cytokine production Source: UniProtKB
Positive regulation of natural killer cell mediated cytotoxicity Source: UniProtKB
Positive regulation of natural killer cell mediated immunity Source: UniProtKB
Positive regulation of natural killer cell proliferation Source: UniProtKB
Positive regulation of T cell mediated cytotoxicity Source: UniProtKB
Positive regulation of TRAIL production Source: UniProtKB
Positive regulation of tumor necrosis factor production Source: UniProtKB
Protection from natural killer cell mediated cytotoxicity Source: UniProtKB
Regulation of natural killer cell mediated immunity Source: UniProtKB
Helical: 306-329
Cytoplasmic: 330-358
The soluble form (sHLA-E) can be partly produced by proteolytic cleavage at the cell surface (shedding) by a matrix metalloproteinase. Alternative splicing is also suggested as a mechanism for generation of sHLA-E, although it remains to be proved.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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