Mouse Anti-HPN Recombinant Antibody (AG84) (V2LY-0524-LY43)

Zaragoza-Huesca, D., Nieto-Olivares, A., García-Molina, F., Ricote, G., Montenegro, S., Sánchez-Cánovas, M., ... & Martínez-Martínez, I. (2022). Implication of Hepsin from primary tumor in the prognosis of colorectal cancer patients. Cancers, 14(13), 3106.

Rodenas, M. C., Peñas-Martínez, J., Pardo-Sánchez, I., Zaragoza-Huesca, D., Ortega-Sabater, C., Peña-García, J., ... & Martínez-Martínez, I. (2023). Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells. Frontiers in Molecular Biosciences, 10, 1182925.

Fang, Y., Yang, H., Hu, G., Lu, J., Zhou, J., Gao, N., ... & Qiao, H. (2022). The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics. Journal of translational medicine, 20(1), 1-17.

Lu, L., Cole, A., Huang, D., Wang, Q., Guo, Z., Yang, W., & Lu, J. (2022). Clinical significance of hepsin and underlying signaling pathways in prostate cancer. Biomolecules, 12(2), 203.

Li, S., Wang, L., Sun, S., & Wu, Q. (2021). Hepsin: a multifunctional transmembrane serine protease in pathobiology. The FEBS journal, 288(18), 5252-5264.

Li, S., Peng, J., Wang, H., Zhang, W., Brown, J. M., Zhou, Y., & Wu, Q. (2020). Hepsin enhances liver metabolism and inhibits adipocyte browning in mice. Proceedings of the National Academy of Sciences, 117(22), 12359-12367.

Tieng, F. Y. F., Abu, N., Sukor, S., Mohd Azman, Z. A., Mahamad Nadzir, N., Lee, L. H., & Ab Mutalib, N. S. (2020). L1CAM, CA9, KLK6, HPN, and ALDH1A1 as potential serum markers in primary and metastatic colorectal cancer screening. Diagnostics, 10(7), 444.

Willbold, R., Wirth, K., Martini, T., Sültmann, H., Bolenz, C., & Wittig, R. (2019). Excess hepsin proteolytic activity limits oncogenic signaling and induces ER stress and autophagy in prostate cancer cells. Cell Death & Disease, 10(8), 601.

Olinger, E., Lake, J., Sheehan, S., Schiano, G., Takata, T., Tokonami, N., ... & Devuyst, O. (2019). Hepsin-mediated processing of uromodulin is crucial for salt-sensitivity and thick ascending limb homeostasis. Scientific reports, 9(1), 12287.

Lee, S. G., Kim, C. H., Sung, S. W., Lee, E. S., Goh, M. S., Yoon, H. Y., ... & Choi, Y. W. (2018). RIPL peptide-conjugated nanostructured lipid carriers for enhanced intracellular drug delivery to hepsin-expressing cancer cells. International journal of nanomedicine, 3263-3278.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols