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Mouse Anti-HS3ST4 Monoclonal Antibody (CBFYH-3205) (CBMAB-H2989-FY)


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Summary

Host Animal
Mouse
Specificity
Mouse, Human
Clone
CBFYH-3205
Antibody Isotype
IgG2
Application
WB

Basic Information

Specificity
Mouse, Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Heparan Sulfate-Glucosamine 3-Sulfotransferase 4
Introduction
This gene encodes the enzyme heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4. This enzyme generates 3-O-sulfated glucosaminyl residues in heparan sulfate. Cell surface heparan sulfate is used as a receptor by herpes simplex virus type 1 (HSV-1), and expression of this gene is thought to play a role in HSV-1 pathogenesis.
Entrez Gene ID
Human9951
Mouse628779
UniProt ID
HumanQ9Y661
MouseD3YVV6
Alternative Names
Heparan Sulfate-Glucosamine 3-Sulfotransferase 4; Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 4; Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 4; Heparan Sulfate 3-O-Sulfotransferase 4; H3-OST-4; 3-OST-4
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity).
Biological Process
Heparan sulfate proteoglycan metabolic process Source: UniProtKB
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-34
Helical: 35-59
Lumenal: 60-456
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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