Sign in or Register   Sign in or Register
  |  

Mouse Anti-HSPB7 (AA 1-171) Recombinant Antibody (CBFYH-2390) (CBMAB-H3403-FY)

This product is mouse antibody that recognizes HSPB7. The antibody CBFYH-2390 can be used for immunoassay techniques such as: ELISA, IHC, WB.
See all HSPB7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-2390
Antibody Isotype
IgG2a
Application
ELISA, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-171

Target

Full Name
heat shock 27kDa protein family, member 7 (cardiovascular)
Introduction
This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma.
Entrez Gene ID
UniProt ID
Alternative Names
Heat Shock Protein Family B (Small) Member 7; Heat Shock 27kDa Protein Family, Member 7 (Cardiovascular); Heat Shock 27kD Protein Family, Member 7 (Cardiovascular); Cardiovascular Heat Shock Protein; CvHSP; Heat Shock Protein Beta-7; HspB7
Biological Process
Heart development Source: InterPro
Regulation of heart contraction Source: ProtInc
Response to unfolded protein Source: ProtInc
Cellular Location
Cytoplasm; Nucleus; Cajal body. Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

Zhang, S., van de Peppel, J., Koedam, M., van Leeuwen, J. P., & van der Eerden, B. C. (2023). HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis. Stem Cell Research & Therapy, 14(1), 1-15.

Muranova, L. K., Shatov, V. M., Slushchev, A. V., & Gusev, N. B. (2022). Is the small heat shock protein HSPB7 (cvHsp) a genuine actin-binding protein?. Biochimie, 202, 103-109.

Muranova, L. K., Shatov, V. M., Bukach, O. V., & Gusev, N. B. (2021). Cardio-vascular heat shock protein (cvHsp, HspB7), an unusual representative of small heat shock protein family. Biochemistry (Moscow), 86, S1-S11.

Muranova, L. K., Shatov, V. M., Slushchev, A. V., & Gusev, N. B. (2021). Quaternary structure and hetero-oligomerization of recombinant human small heat shock protein HspB7 (cvHsp). International Journal of Molecular Sciences, 22(15), 7777.

Kim, J., Aydemir, T. B., Jimenez-Rondan, F. R., Ruggiero, C. H., Kim, M. H., & Cousins, R. J. (2020). Deletion of metal transporter Zip14 (Slc39a14) produces skeletal muscle wasting, endotoxemia, Mef2c activation and induction of miR-675 and Hspb7. Scientific Reports, 10(1), 4050.

Jin, C., Shuai, T., & Tang, Z. (2020). HSPB7 regulates osteogenic differentiation of human adipose derived stem cells via ERK signaling pathway. Stem Cell Research & Therapy, 11(1), 1-13.

Wu, D., Vonk, J. J., Salles, F., Vonk, D., Haslbeck, M., Melki, R., ... & Kampinga, H. H. (2019). The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation–suppressing activity. Journal of Biological Chemistry, 294(25), 9985-9994.

Surya, S. L., Long, M. J., Urul, D. A., Zhao, Y., Mercer, E. J., EIsaid, I. M., ... & Aye, Y. (2018). Cardiovascular small heat shock protein HSPB7 is a kinetically privileged reactive electrophilic species (RES) sensor. ACS chemical biology, 13(7), 1824-1831.

Mercer, E. J., Lin, Y. F., Cohen-Gould, L., & Evans, T. (2018). Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis. Developmental biology, 435(1), 41-55.

Naderi, A. (2018). SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies. Molecular Oncology, 12(5), 724-755.

Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Have you used Mouse Anti-HSPB7 (AA 1-171) Recombinant Antibody (CBFYH-2390)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare