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Mouse Anti-HUNK (AA 615-714) Recombinant Antibody (CBFYH-2553) (CBMAB-H3574-FY)

This product is mouse antibody that recognizes HUNK. The antibody CBFYH-2553 can be used for immunoassay techniques such as: ELISA, WB.
See all HUNK antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-2553
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 615-714

Target

Full Name
HORMONALLY UP-REGULATED NEU-ASSOCIATED KINASE
Introduction
HUNK (Hormonally Up-Regulated Neu-Associated Kinase) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is PRKAA2.
Entrez Gene ID
30811
UniProt ID
P57058
Alternative Names
Hormonally Up-Regulated Neu-Associated Kinase; Hormonally Upregulated Neu-Associated Kinase; EC 2.7.11.1; B19; Hormonally Up-Regulated Neu Tumor-Associated Kinase; Hormonally Upregulated Neu Tumor-Associated Kinase
Biological Process
Intracellular signal transduction Source: GO_Central
Multicellular organism development Source: ProtInc
Protein phosphorylation Source: GO_Central
Signal transduction Source: ProtInc

Dilday, T., Abt, M., Sintim, H., Sandusky, G., & Yeh, E. S. (2023). Identification and Testing of a Novel HUNK Inhibitor.

Solis, N. R., Yeh, E. S., Kaplan, M. H., & Cannon, A. M. (2023). HUNK regulation of IL-4 promotes polarization of tumor-associated macrophages in TNBC tumor microenvironment.

Ramos Solis, N., & Yeh, E. S. (2022). HUNK regulation of interleukin 4 in triple negative breast cancer. The FASEB Journal, 36.

Ramos-Solis, N., Dilday, T., Kritikos, A. E., & Yeh, E. S. (2022). HUNK Gene Alterations in Breast Cancer. Biomedicines, 10(12), 3072.

Dilday, T., Ramos, N., & Yeh, E. (2020). HUNK signaling in metastatic breast cancer. Oncoscience, 7(5-6), 30.

Williams, C. B., Phelps-Polirer, K., Dingle, I. P., Williams, C. J., Rhett, M. J., Eblen, S. T., ... & Yeh, E. S. (2020). HUNK phosphorylates EGFR to regulate breast cancer metastasis. Oncogene, 39(5), 1112-1124.

Zambrano, J. N., Eblen, S. T., Abt, M., Rhett, J. M., Muise-Helmericks, R., & Yeh, E. S. (2019). HUNK phosphorylates rubicon to support autophagy. International Journal of Molecular Sciences, 20(22), 5813.

Lakshmanan, A., Rabaglia, M., Das, R., Schueler, K., Stapleton, D., Simonett, S., ... & Attie, A. (2018). Hunk, a Serine/Threonine Protein Kinase, Regulates Insulin Secretion from Pancreatic Islets. The FASEB Journal, 32, 670-15.

Zambrano, J. N., Williams, C. J., Williams, C. B., Hedgepeth, L., Burger, P., Dilday, T., ... & Yeh, E. S. (2018). Staurosporine, an inhibitor of hormonally up-regulated neu-associated kinase. Oncotarget, 9(89), 35962.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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