Mouse Anti-IFNL1 Recombinant Antibody (A543) (CBMAB-AP10866LY)

Name: Mouse Anti-IFNL1 Recombinant Antibody (A543)
SKU: CBMAB-AP10866LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

A543

Application

ELISA, WB

Immunogen

Fusion protein of IL-29

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

Affinity purity

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Interferon Lambda 1

Introduction

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]

Entrez Gene ID

282618

UniProt ID

Q8IU54

Alternative Names

Interferon Lambda 1

Function

E-AB-27211

Biological Process

Defense response to virus Source: UniProtKB
Innate immune response Source: GO_Central
Negative regulation of cell population proliferation Source: UniProtKB
Negative regulation of interleukin-13 production Source: UniProtKB
Negative regulation of interleukin-5 production Source: UniProtKB
Negative regulation of memory T cell differentiation Source: UniProtKB
Negative regulation of T cell differentiation Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of type 2 immune response Source: UniProtKB
Positive regulation of immune response Source: UniProtKB
Positive regulation of interferon-gamma production Source: UniProtKB
Positive regulation of MHC class I biosynthetic process Source: UniProtKB
Positive regulation of receptor signaling pathway via JAK-STAT Source: UniProtKB
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of tyrosine phosphorylation of STAT protein Source: UniProtKB
Receptor signaling pathway via JAK-STAT Source: InterPro

Cellular Location

Secreted

Chua, K. J., Ling, H., Hwang, I. Y., Lee, H. L., March, J. C., Lee, Y. S., & Chang, M. W. (2022). An Engineered Probiotic Produces a Type III Interferon IFNL1 and Reduces Inflammations in in vitro Inflammatory Bowel Disease Models. ACS Biomaterials Science & Engineering.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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