Rabbit Anti-IMMP1L Recombinant Antibody (D33A2) (CBMAB-CP1168-LY)

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Basic Information

Host Animal
Rabbit
Clone
D33A2
Application
WB, IP
Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human IMP1 protein.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Inner Mitochondrial Membrane Peptidase Subunit 1
Introduction
The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008]
Entrez Gene ID
Human196294
Mouse66541
Rat691145
UniProt ID
HumanQ96LU5
MouseQ9CQU8
RatD3ZWF3
Alternative Names
Inner Mitochondrial Membrane Peptidase Subunit 1
Function
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
Biological Process
Protein processing involved in protein targeting to mitochondrionManual Assertion Based On ExperimentIBA:GO_Central
Signal peptide processingIEA:InterPro
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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