IMMP1L

The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008]

Inner Mitochondrial Membrane Peptidase Subunit 1

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.

Protein processing involved in protein targeting to mitochondrionManual Assertion Based On ExperimentIBA:GO_Central
Signal peptide processingIEA:InterPro

Mitochondrion inner membrane