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Mouse Anti-ITGA2B Recombinant Antibody (10E5) (CBMAB-0008-CN)

This product is a mouse antibody that recognizes ITGA2B of human. The antibody 10E5 can be used for immunoassay techniques such as: ELISA, FC, BL, IP.
Host Species
Mouse
Application
ELISA, FC, Blocking, IP
Immunogen
Human platelets full length protein
Antibody Isotype
IgG2a
Specificity
Human, Primate
Clone
10E5
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes a member of the integrin alpha chain family of proteins. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain.
Alternative Name
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-0008-CN
Conjugates
Size
Price $
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Second antibody and isotype control