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Mouse Anti-IVL Recombinant Antibody (CBYY-I0046) (CBMAB-I0119-YY)

This product is Mouse antibody that recognizes IVL. The antibody CBYY-I0046 can be used for immunoassay techniques such as: IHC-P, IF
See all IVL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-I0046
Antibody Isotype
IgG1, κ
Application
IHC-P, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.1 mg/ml BSA
Preservative
0.05% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Involucrin
Introduction
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and ca
Entrez Gene ID
3713
UniProt ID
P07476
Alternative Names
Involucrin
Function
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
Biological Process
Isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysineManual Assertion Based On ExperimentTAS:UniProtKB
KeratinizationIEA:UniProtKB-KW
Keratinocyte differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Peptide cross-linkingManual Assertion Based On ExperimentIDA:UniProtKB
Response to UV-BManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm. Constituent of the scaffolding of the cornified envelope.
PTM
Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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