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Rabbit Anti-JARID2 Recombinant Antibody (13HCLC) (CBMAB-0051-WJ)

This product is a rabbit antibody that recognizes JARID2. The antibody 13HCLC can be used for immunoassay techniques such as: FC, ICC, IF, WB.
Host Species
Rabbit
Application
FC, ICC, IF, WB
Antibody Isotype
IgG
Specificity
Human, Mouse
Clone
13HCLC
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. Diseases associated with JARID2 include Reticuloendotheliosis and Spina Bifida Occulta. Among its related pathways are Mesodermal Commitment Pathway and Gene Expression. An important paralog of this gene is KDM5B.
Alternative Name
JARID2; jumonji, AT rich interactive domain 2; JMJ, jumonji (mouse) homolog, Jumonji, AT rich interactive domain 2; protein Jumonji; jumonji homolog; jumonji-like protein; jumonji/ARID domain-containing protein 2; JMJ
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-0051-WJ
Conjugates
Size
Price $
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Second antibody and isotype control