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Rabbit Anti-JUNB Recombinant Antibody (15HCLC) (CBMAB-0065-WJ)

This product is a rabbit antibody that recognizes JUNB. The antibody 15HCLC can be used for immunoassay techniques such as: ChIP, ICC, IF, WB.
See all JUNB antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
15HCLC
Antibody Isotype
IgG
Application
ChIP, ICC, IF, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
JunB proto-oncogene, AP-1 transcription factor subunit
Introduction
JUNB (JunB Proto-Oncogene, AP-1 Transcription Factor Subunit) is a Protein Coding gene. Diseases associated with JUNB include Anaplastic Large Cell Lymphoma and Fumarate Hydratase Deficiency. Among its related pathways are Cytokine Signaling in Immune system and Toll-like receptor signaling pathway. An important paralog of this gene is JUN. Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5-TGA[CG]TCA-3.
Entrez Gene ID
3726
UniProt ID
P17275
Alternative Names
JUNB; jun B proto-oncogene; transcription factor jun-B; activator protein 1; AP-1
Function
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity).
Biological Process
Cellular response to calcium ionIEA:Ensembl
DecidualizationIEA:Ensembl
Embryonic process involved in female pregnancyIEA:Ensembl
Labyrinthine layer blood vessel developmentIEA:Ensembl
Osteoblast differentiationIEA:Ensembl
Osteoblast proliferationIEA:Ensembl
Osteoclast differentiationIEA:Ensembl
Positive regulation of cell differentiationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:CAFA
Regulation of cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Trophectodermal cell differentiationIEA:Ensembl
VasculogenesisIEA:Ensembl
Cellular Location
Nucleus
PTM
Ubiquitinated by ITCH, leading to its degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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