JUNB

JUNB (JunB Proto-Oncogene, AP-1 Transcription Factor Subunit) is a Protein Coding gene. Diseases associated with JUNB include Anaplastic Large Cell Lymphoma and Fumarate Hydratase Deficiency. Among its related pathways are Cytokine Signaling in Immune system and Toll-like receptor signaling pathway. An important paralog of this gene is JUN. Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5-TGA[CG]TCA-3.

JunB proto-oncogene, AP-1 transcription factor subunit

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity).

Cellular response to calcium ionIEA:Ensembl
DecidualizationIEA:Ensembl
Embryonic process involved in female pregnancyIEA:Ensembl
Labyrinthine layer blood vessel developmentIEA:Ensembl
Osteoblast differentiationIEA:Ensembl
Osteoblast proliferationIEA:Ensembl
Osteoclast differentiationIEA:Ensembl
Positive regulation of cell differentiationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:CAFA
Regulation of cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Trophectodermal cell differentiationIEA:Ensembl
VasculogenesisIEA:Ensembl

Nucleus

Ubiquitinated by ITCH, leading to its degradation.