Rabbit Anti-JUNB Recombinant Antibody (C37F9) (CBMAB-CP1276-LY)

Name: Rabbit Anti-JUNB Recombinant Antibody (C37F9)
SKU: CBMAB-CP1276-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

C37F9

Application

WB, IP, IHC-P, IF (ICC), CIP

Immunogen

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro169 of human JunB.

Specificity

Human, Mouse, Rat, Monkey

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

100 µg/ml BSA, 50% glycerol

Preservative

0.02% sodium azide

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

JunB proto-oncogene, AP-1 transcription factor subunit

Entrez Gene ID

Human	3726
Mouse	16477
Rat	24517
Monkey	717837

UniProt ID

Human	P17275
Mouse	P09450
Rat	P24898
Monkey	F6U5C5

Alternative Names

AP-1

Function

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity).

Biological Process

Cellular response to calcium ionIEA:Ensembl
DecidualizationIEA:Ensembl
Embryonic process involved in female pregnancyIEA:Ensembl
Labyrinthine layer blood vessel developmentIEA:Ensembl
Osteoblast differentiationIEA:Ensembl
Osteoblast proliferationIEA:Ensembl
Osteoclast differentiationIEA:Ensembl
Positive regulation of cell differentiationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:CAFA
Regulation of cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Trophectodermal cell differentiationIEA:Ensembl
VasculogenesisIEA:Ensembl

Cellular Location

Nucleus

PTM

Ubiquitinated by ITCH, leading to its degradation.

Ren, F., Cai, X., Yao, Y., & Fang, G. Y. (2023). JunB: a paradigm for Jun family in immune response and cancer. Frontiers in Cellular and Infection Microbiology, 13, 1222265.

Chen, H., & Chen, G. (2022). Dissecting immunosuppressive cell communication patterns reveals JunB proto-oncogene (JUNB) shaping a non-inflamed tumor microenvironment. Frontiers in Genetics, 13, 883583.

Yan, P., Zhou, B., Ma, Y., Wang, A., Hu, X., Luo, Y., ... & Mao, J. (2020). Tracking the important role of JUNB in hepatocellular carcinoma by single‑cell sequencing analysis. Oncology letters, 19(2), 1478-1486.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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