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Mouse Anti-KAT14 Recombinant Antibody (2221C4a) (CBMAB-C0670-LY)

This product is antibody recognizes KAT14. The antibody 2221C4a immunoassay techniques such as: DB, WB.
See all KAT14 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2221C4a
Antibody Isotype
IgG1
Application
DB, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Lysine Acetyltransferase 14
Introduction
CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]
Entrez Gene ID
57325
UniProt ID
Q9H8E8
Alternative Names
Lysine Acetyltransferase 14; ADA2A-Containing Complex Subunit 2; CSRP2-Binding Protein; CSRP2BP; CRP2BP; ATAC2; Cysteine Rich Protein 2 Binding Protein; Cysteine-Rich Protein 2-Binding Protein; ATAC Component 2 Homolog (Drosophila);
Function
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.
Biological Process
Histone H3 acetylationManual Assertion Based On ExperimentIDA:BHF-UCL
Histone H3-K14 acetylationManual Assertion Based On ExperimentIDA:ComplexPortal
Regulation of cell cycleManual Assertion Based On ExperimentIMP:ComplexPortal
Regulation of cell divisionManual Assertion Based On ExperimentIDA:ComplexPortal
Regulation of histone deacetylationManual Assertion Based On ExperimentIMP:ComplexPortal
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:ComplexPortal
Regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIMP:ComplexPortal
Regulation of tubulin deacetylationManual Assertion Based On ExperimentIMP:ComplexPortal
Cellular Location
Nucleus; Cytoplasm. Mainly nuclear.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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