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Rabbit Anti-KCNH3 Recombinant Antibody (EG1756) (CBMAB-EN2095-LY)

The product is antibody recognizes KCNH3. The antibody EG1756 immunoassay techniques such as: WB: 1:500~1:3000 ELISA: 1:40000.
See all KCNH3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1756
Antibody Isotype
IgG
Application
WB: 1:500~1:3000 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from Internal of human KCNH3.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
potassium voltage-gated channel subfamily H member 3
Introduction
The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
Human23416
Mouse16512
Rat27150
UniProt ID
HumanQ9ULD8
MouseQ9WVJ0
RatO89047
Alternative Names
BEC1; ELK2; Kv12.2
Function
Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly.
Biological Process
Potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Potassium ion transportManual Assertion Based On ExperimentTAS:UniProtKB
Regulation of ion transmembrane transportIEA:UniProtKB-KW
Regulation of membrane potentialManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-228
Helical: 229-249
Extracellular: 250-259
Helical: 260-280
Cytoplasmic: 281-302
Helical: 303-323
Extracellular: 324-331
Helical: 332-352
Cytoplasmic: 353-361
Helical: 362-382
Extracellular: 383-453
Pore-forming: 454-474
Extracellular: 475-479
Helical: 480-500
Cytoplasmic: 501-1083
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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