Fusion protein aa 1168-1237 of rat Slo2.2 (Slack; NP_068625)
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
Potassium Sodium-Activated Channel Subfamily T Member 1; Potassium Channel, Sodium Activated Subfamily T, Member 1; Sequence Like A Calcium-Activated K+ Channel; Potassium Channel, Subfamily T, Member 1; KCa4.1; Potassium Channel Subfamily T Member 1; BA100C15.2;