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Mouse Anti-KIF13B Recombinant Antibody (6E11) (CBMAB-K0844-LY)

This product is antibody recognizes KIF13B. The antibody 6E11 immunoassay techniques such as: WB, IP, ELISA.
See all KIF13B antibodies
Published Data
Fig.1 Kif13b is upregulated during serum deprivation and localizes to the base and along the primary cilium.
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Fig.2 Cells treated with control- or KIF13B siRNA were immunoblotted and proteins detected with indicated antibodies.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
6E11
Antibody Isotype
IgG
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Kinesin Family Member 13B
Introduction
Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
Entrez Gene ID
23303
UniProt ID
Q9NQT8
Alternative Names
Kinesin Family Member 13B; Kinesin-Like Protein GAKIN; GAKIN; Guanylate Kinase Associated Kinesin; Kinesin-Like Protein KIF13B; Kinesin 13B; KIAA0639;
Function
Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
Biological Process
Microtubule-based movementManual Assertion Based On ExperimentIBA:GO_Central
Protein targetingManual Assertion Based On ExperimentTAS:UniProtKB
Regulation of axonogenesisManual Assertion Based On ExperimentIDA:UniProtKB
Signal transduction1 PublicationNAS:UniProtKB
T cell activation1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm, cytoskeleton; Cell projection, axon. accumulates at the distal part of the microtubules in the tips of axons, but not of dendrites.
PTM
Phosphorylated at Ser-1381 and Ser-1410 by MARK2, promoting interaction with 14-3-3 and inhibiting microtubule-dependent accumulation and formation of axons.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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