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Mouse Anti-KIF13B Recombinant Antibody (7H5) (CBMAB-0695-CN)

This product is a mouse antibody that recognizes KIF13B of human. The antibody 7H5 can be used for immunoassay techniques such as: ELISA, MA.
See all KIF13B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7H5
Antibody Isotype
IgG1
Application
ELISA, MA

Basic Information

Immunogen
Recombinant full length protein of KIF13B
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Kinesin Family Member 13B
Introduction
Kinesin family member 13B is a protein that in humans is encoded by the KIF13B gene. This protein is involved in reorganization of the cortical cytoskeleton. It regulates axon formation by promoting the formation of extra axons. This protein may also be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
Entrez Gene ID
23303
UniProt ID
Q9NQT8
Alternative Names
GAKIN
Function
Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
Biological Process
Microtubule-based movementManual Assertion Based On ExperimentIBA:GO_Central
Protein targetingManual Assertion Based On ExperimentTAS:UniProtKB
Regulation of axonogenesisManual Assertion Based On ExperimentIDA:UniProtKB
Signal transduction1 PublicationNAS:UniProtKB
T cell activation1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm, cytoskeleton; Cell projection, axon. accumulates at the distal part of the microtubules in the tips of axons, but not of dendrites.
PTM
Phosphorylated at Ser-1381 and Ser-1410 by MARK2, promoting interaction with 14-3-3 and inhibiting microtubule-dependent accumulation and formation of axons.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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