Sign in or Register   Sign in or Register
  |  

Mouse Anti-KIF16B Recombinant Antibody (2B5) (CBMAB-K0846-LY)

This product is antibody recognizes KIF16B. The antibody 2B5 immunoassay techniques such as: ELISA, WB.
See all KIF16B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2B5
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
KIF16B (AAH34984, 65 a.a. ~ 174 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: DDLKDPIKIS IPRYVLCGQG KDAHFEFEVK LAALEFPPKK LFGNKDERVI AERRSHLEKY LRDFFSVMLQ SATSPLHINK VGLTLSKHTI CEFSPFFKKG VFDYSSHGTG
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
kinesin family member 16B
Introduction
The protein encoded by this gene is a kinesin-like protein that may be involved in intracellular trafficking. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Entrez Gene ID
55614
UniProt ID
Q96L93
Alternative Names
Kinesin Family Member 16B; C20orf23; SNX23; Testis Secretory Sperm-Binding Protein Li 201a; Chromosome 20 Open Reading Frame 23; Kinesin-Like Protein KIF16B;
Function
Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.
Biological Process
Early endosome to late endosome transportManual Assertion Based On ExperimentIMP:UniProtKB
Endoderm developmentISS:UniProtKB
Epidermal growth factor receptor signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Fibroblast growth factor receptor signaling pathwayISS:UniProtKB
Formation of primary germ layerISS:UniProtKB
Golgi to endosome transportISS:UniProtKB
Microtubule-based movementManual Assertion Based On ExperimentIBA:GO_Central
Receptor catabolic processManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of receptor recyclingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm, cytoskeleton; Early endosome membrane; Cytoplasm; Cytoplasm, cytoskeleton, spindle. It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KIF16B Recombinant Antibody (2B5)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare