Sign in or Register   Sign in or Register
  |  

Mouse Anti-KLRC3 Recombinant Antibody (3D5) (CBMAB-K1406-LY)

This product is antibody recognizes KLRC3. The antibody 3D5 immunoassay techniques such as: ELISA, WB.
See all KLRC3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3D5
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
KLRC3 (NP_002252, 132 a.a. ~ 241 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
killer cell lectin-like receptor subfamily C, member 3
Introduction
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Entrez Gene ID
3823
UniProt ID
Q07444
Alternative Names
Killer Cell Lectin Like Receptor C3; Killer Cell Lectin-Like Receptor Subfamily C; Member 3; NKG2-E-Activating NK Receptor; NK Cell Receptor E; NKG2E; NKG2-E Type II Integral Membrane Protein; NKG2-E;
Function
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Biological Process
Cellular defense responseManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of natural killer cell mediated cytotoxicityManual Assertion Based On ExperimentIBA:GO_Central
Stimulatory C-type lectin receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-70
Helical: 71-93
Extracellular: 94-240
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KLRC3 Recombinant Antibody (3D5)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare