Mouse Anti-KRT13 Recombinant Antibody (CBYY-C2821) (CBMAB-C4262-YY)

This product is mouse antibody that recognizes KRT13. The antibody CBYY-C2821 can be used for immunoassay techniques such as: IF, IHC, WB
See all KRT13 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse, Rabbit, Rat

Clone

CBYY-C2821

Antibody Isotype

IgG2b

Application

IF, IHC, WB

Basic Information

Immunogen

Cytokeratin preparation from human esophagus

Specificity

Human, Mouse, Rabbit, Rat

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Culture supernatant

Concentration

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Keratin 13

Entrez Gene ID

Human	3860
Mouse	16663
Rat	287699
Rabbit	100344183

UniProt ID

Human	P13646
Rat	Q6IFV4
Mouse	P08730

Alternative Names

B-CK, BCKB, CPK-B, HEL-211, HEL-S-29, CKB

Biological Process

Cytoskeleton organizationManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytosol
Extracellular exosome
Intermediate filament cytoskeleton
Keratin filament
Nucleus

Involvement in disease

White sponge nevus 2 (WSN2):
A rare disorder characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.

PTM

O-glycosylated; glycans consist of single N-acetylglucosamine residues.

References

Yin, L., Li, Q., Mrdenovic, S., Chu, G. C. Y., Wu, B. J., Bu, H., ... & Chung, L. W. (2022). KRT13 promotes stemness and drives metastasis in breast cancer through a plakoglobin/c-Myc signaling pathway. Breast Cancer Research, 24(1), 1-13.

Simonson, L., Vold, S., Mowers, C., Massey, R. J., Ong, I. M., Longley, B. J., & Chang, H. (2020). Keratin 13 deficiency causes white sponge nevus in mice. Developmental biology, 468(1-2), 146-153.

Yin, L., Chu, G. C. Y., Li, Q., Yin, L., Lewis, M., Tighiouart, M., ... & Zhau, H. E. (2018). KRT13 promotes stemness and drives metastasis in breast cancer through direct interaction with plakoglobin-desmoplakin complexes regulating c-Myc signaling pathway. Cancer Research, 78(13_Supplement), 5002-5002.

Westin, M., Rekabdar, E., Blomstrand, L., Klintberg, P., Jontell, M., & Robledo‐Sierra, J. (2018). Mutations in the genes for keratin‐4 and keratin‐13 in Swedish patients with white sponge nevus. Journal of Oral Pathology & Medicine, 47(2), 152-157.

Hatta, M., Miyake, Y., Uchida, K., & Yamazaki, J. (2018). Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line. Biochemical and biophysical research communications, 496(2), 381-386.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-KRT13 Recombinant Antibody (CBYY-C2821)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-KRT13 Recombinant Antibody (12E6)

Mouse Anti-KRT13 Recombinant Antibody (Ks13-1)

Mouse Anti-KRT13 Recombinant Antibody (Ks13.1)

Mouse Anti-KRT13 Recombinant Antibody (PT0075)

Mouse Anti-KRT13 Recombinant Antibody (AE3)

Mouse Anti-KRT13 Recombinant Antibody (CBWJC-3984)

Mouse Anti-KRT13 Recombinant Antibody (5F83)

Mouse Anti-KRT13 Recombinant Antibody (CBWJC-3985)

Mouse Anti-KRT13 Recombinant Antibody (Ks 13.1)

Mouse Anti-KRT13 Recombinant Antibody (AE8)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: