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Mouse Anti-KRT7 Recombinant Antibody (K72.7) (CBMAB-K1971-LY)

This product is antibody recognizes KRT7. The antibody K72.7 immunoassay techniques such as: IHC-P, IF/ICC, FC.
See all KRT7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
K72.7
Antibody Isotype
IgG1, κ
Application
IHC-P, IF/ICC, FC

Basic Information

Immunogen
Semi-purified cytokeratin preparation
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.05% BSA
Preservative
0.05% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Keratin 7
Introduction
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Entrez Gene ID
UniProt ID
Alternative Names
Keratin 7; Sarcolectin; Keratin; 55K Type II Cytoskeletal; Keratin; Type II Cytoskeletal 7; Type-II Keratin Kb7; Keratin 7; Type II; Cytokeratin 7; CK-7; SCL;
Function
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Cellular Location
Cytoplasm
PTM
Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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