Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1045) (CBMAB-L0459-YJ)

Name: Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1045)
SKU: CBMAB-L0459-YJ
Rating: 5 (1 reviews)

See all LACTB2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJL-1045

Application

FC, IHC-P, WB

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.3, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

lactamase, beta 2

Introduction

Gene Ontology (GO) annotations related to LACTB2 include hydrolase activity. LACTB2 cleaves preferentially 3 to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3 -OH group. LACTB2 has no activity with double-stranded RNA or DNA. LACTB2 is required for normal mitochondrial function and cell viability.

Entrez Gene ID

51110

UniProt ID

Q53H82

Function

Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

Biological Process

RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Mitochondrion matrix

Chen, Q., Zheng, W., Zhu, L., Liu, H., Song, Y., Hu, S., ... & Shao, C. (2021). LACTB2 renders radioresistance by activating PINK1/Parkin-dependent mitophagy in nasopharyngeal carcinoma. Cancer letters, 518, 127-139.

Harwood, J. C., Leonenko, G., Sims, R., Escott-Price, V., Williams, J., & Holmans, P. (2020). Monocyte-specific changes in gene expression implicate LACTB2 and PLIN2 in Alzheimer’s disease. bioRxiv, 2020-06.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1045)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-LACTB2 Recombinant Antibody (4E7) (CAT#: CBMAB-L0463-YJ)

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1044) (CAT#: CBMAB-L0458-YJ)

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1046) (CAT#: CBMAB-L0460-YJ)

Mouse Anti-LACTB2 Recombinant Antibody (3A5) (CAT#: CBMAB-L0462-YJ)

Mouse Anti-LACTB2 Recombinant Antibody (2F9) (CAT#: CBMAB-L0461-YJ)

Mouse Anti-LACTB2 Recombinant Antibody (4F7) (CAT#: CBMAB-L0464-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry