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LACTB2

Gene Ontology (GO) annotations related to LACTB2 include hydrolase activity. LACTB2 cleaves preferentially 3 to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3 -OH group. LACTB2 has no activity with double-stranded RNA or DNA. LACTB2 is required for normal mitochondrial function and cell viability.
Full Name
lactamase, beta 2
Function
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
Biological Process
RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Mitochondrion matrix

Anti-LACTB2 antibodies

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Mouse Anti-LACTB2 Recombinant Antibody (4F7) (CBMAB-L0464-YJ)

Datasheet SDS
Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F7
Application*: WB

Mouse Anti-LACTB2 Recombinant Antibody (4E7) (CBMAB-L0463-YJ)

Datasheet SDS
Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E7
Application*: F, WB

Mouse Anti-LACTB2 Recombinant Antibody (3A5) (CBMAB-L0462-YJ)

Datasheet SDS
Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A5
Application*: F, IH, WB

Mouse Anti-LACTB2 Recombinant Antibody (2F9) (CBMAB-L0461-YJ)

Datasheet SDS
Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2F9
Application*: F, P, WB

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1046) (CBMAB-L0460-YJ)

Datasheet SDS
Target: LACTB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1046
Application*: E, WB

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1045) (CBMAB-L0459-YJ)

Datasheet SDS
Target: LACTB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1045
Application*: F, P, WB

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1044) (CBMAB-L0458-YJ)

Datasheet SDS
Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1044
Application*: WB, F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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