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LACTB2

Gene Ontology (GO) annotations related to LACTB2 include hydrolase activity. LACTB2 cleaves preferentially 3 to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3 -OH group. LACTB2 has no activity with double-stranded RNA or DNA. LACTB2 is required for normal mitochondrial function and cell viability.
Full Name
lactamase, beta 2
Function
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
Biological Process
RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Mitochondrion matrix
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Anti-LACTB2 antibodies

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Mouse Anti-LACTB2 Recombinant Antibody (4F7) (CBMAB-L0464-YJ)

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Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F7
Application*: WB
Datasheet SDS

Mouse Anti-LACTB2 Recombinant Antibody (4E7) (CBMAB-L0463-YJ)

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Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4E7
Application*: F, WB
Datasheet SDS

Mouse Anti-LACTB2 Recombinant Antibody (3A5) (CBMAB-L0462-YJ)

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Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A5
Application*: F, IH, WB
Datasheet SDS

Mouse Anti-LACTB2 Recombinant Antibody (2F9) (CBMAB-L0461-YJ)

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Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2F9
Application*: F, P, WB
Datasheet SDS

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1046) (CBMAB-L0460-YJ)

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Target: LACTB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1046
Application*: E, WB
Datasheet SDS

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1045) (CBMAB-L0459-YJ)

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Target: LACTB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1045
Application*: F, P, WB
Datasheet SDS

Mouse Anti-LACTB2 Recombinant Antibody (CBYJL-1044) (CBMAB-L0458-YJ)

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Target: LACTB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1044
Application*: WB, F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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