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Rabbit Anti-LAMTOR4 Recombinant Antibody (CBWJC-4119) (CBMAB-C5463WJ)

This product is a Rabbit antibody that recognizes LAMTOR4. This antibody CBWJC-4119 can be used for immunoassay techniques such as: WB, IP, IF.
See all LAMTOR4 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat, Monkey
Clone
CBWJC-4119
Antibody Isotype
IgG
Application
WB, IP, IF

Basic Information

Specificity
Human, Mouse, Rat, Monkey
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 4
Introduction
LAMTOR4 (Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 4) is a Protein Coding gene. Among its related pathways are Gene Expression and RET signaling. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and protein-containing complex scaffold activity.
Entrez Gene ID
Human389541
Mouse66096
Rat360776
Monkey719122
UniProt ID
HumanQ0VGL1
MouseQ8CF66
RatD4AD29
MonkeyG7P0C8
Alternative Names
C7orf59
Function
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.
Biological Process
Cellular response to amino acid stimulusManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of TOR signalingManual Assertion Based On ExperimentIMP:UniProtKB
Protein localization to lysosomeManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of catalytic activityIEA:GOC
Regulation of cell sizeManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Lysosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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