Human Anti-LGALS2 Recombinant Antibody (H3F3D1) (CBMAB-H3655-FY)

This product is human antibody that recognizes LGALS2. The antibody H3F3D1 can be used for immunoassay techniques such as: Immunoassay.
See all LGALS2 antibodies

Datasheet

Summary

Host Animal

Human

Specificity

Mouse

Clone

H3F3D1

Antibody Isotype

IgG1

Application

Immunoassay

Basic Information

Specificity

Mouse

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Galectin 2

Introduction

The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha.

Entrez Gene ID

107753

UniProt ID

Q9CQW5

Alternative Names

AI324147; 2200008F12Rik

Function

This protein binds beta-galactoside. Its physiological function is not yet known.

Biological Process

Cell-cell adhesionManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of inflammatory responseIEA:Ensembl
T cell homeostasisManual Assertion Based On ExperimentIDA:ComplexPortal

Cellular Location

Cytoplasm
Galectin complex

References

He, S., Ji, Z., Zhang, Q., Zhang, X., Chen, J., Hu, J., ... & Ding, Y. (2023). Investigation of LGALS2 expression in the TCGA database reveals its clinical relevance in breast cancer immunotherapy and drug resistance. Scientific Reports, 13(1), 17445.

Jiang, H., Sun, Q., Huang, Z., Chen, H., Chen, L., & He, X. (2023). LGALS2 and EGR1: markers of endometriosis for predictive, preventive and personalized medicine.

Ji, P., Gong, Y., Jin, M. L., Wu, H. L., Guo, L. W., Pei, Y. C., ... & Shao, Z. M. (2022). In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer. Science Advances, 8(26), eabl8247.

Chetry, M., Bhandari, A., Feng, R., Song, X., Wang, P., & Lin, J. (2022). Overexpression of galectin2 (LGALS2) predicts a better prognosis in human breast cancer. American Journal of Translational Research, 14(4), 2301.

Xu, D., Guo, L., Zhang, S., & Hou, Q. (2022). LGALS2 suppresses the progression of papillary thyroid carcinoma by regulating the PI3K/AKT pathway. Gland Surgery, 11(9), 1518.

Xu, W. D., Wu, Q., He, Y. W., Huang, A. F., Lan, Y. Y., Fu, L., ... & Liu, X. Y. (2021). Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis. Cellular Immunology, 368, 104419.

Li, H., Zhao, L., Lau, Y. S., Zhang, C., & Han, R. (2021). Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth. Oncogene, 40(1), 177-188.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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