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Mouse Anti-LGALS7 Recombinant Antibody (CBLG1-2373) (CBMAB-G6325-LY)

This product is antibody recognizes LGALS7 . The antibody CBLG1-2373 immunoassay techniques such as: ICC, IHC-F/P, ELISA (EIA), WB.
See all LGALS7 antibodies

Summary

Host Animal
Mouse
Specificity
Rat
Clone
CBLG1-2373
Antibody Isotype
IgG
Application
ICC, IHC-F/P, ELISA (EIA), WB

Basic Information

Immunogen
The antibody is a mouse monoclonal antibody raised against GAL7. It has been selected for its ability to recognize GAL7 in immunohistochemical staining andwestern blotting
Specificity
Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% NaN3
Concentration
0.5 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
lectin, galactoside-binding, soluble, 7
Introduction
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19.
Entrez Gene ID
29518
UniProt ID
P97590
Function
Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.
Biological Process
Apoptotic processIEA:UniProtKB-KW
Heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of CD4-positive, alpha-beta T cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of interferon-gamma productionManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of gene expressionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Nucleus
Secreted
May be secreted by a non-classical secretory pathway.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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