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LGALS7

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq]

Full Name

lectin, galactoside-binding, soluble, 7

Function

Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Biological Process

Apoptotic processIEA:UniProtKB-KW
Heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of CD4-positive, alpha-beta T cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of interferon-gamma productionManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of gene expressionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Nucleus
Secreted
May be secreted by a non-classical secretory pathway.

Anti-LGALS7 antibodies

Rabbit Anti-LGALS7 Recombinant Antibody (CBYJL-1532) (CBMAB-L1302-YJ)

SDS

Target: LGALS7

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-1532

Application*: WB, IP, P, IC

Mouse Anti-LGALS7 Recombinant Antibody (32) (CBMAB-AP2997LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Rat

Clone: 32

Application*: ICC, IHC, IP, WB

Mouse Anti-LGALS7 Recombinant Antibody (198614) (CBMAB-G1123-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 198614

Application*: WB

Rat Anti-LGALS7 Recombinant Antibody (212923) (CBMAB-G1124-LY)

SDS

Target: LGALS7

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 212923

Application*: WB

Mouse Anti-LGALS7 Recombinant Antibody (950723) (CBMAB-G1125-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 950723

Application*: WB

Mouse Anti-LGALS7 Recombinant Antibody (950756) (CBMAB-G1126-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 950756

Application*: WB

Rat Anti-LGALS7 Recombinant Antibody (14L457) (CBMAB-G6318-LY)

SDS

Target: LGALS7

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: 14L457

Application*: IH, WB

Rat Anti-LGALS7 Recombinant Antibody (RM0083-8J52) (CBMAB-G6320-LY)

SDS

Target: LGALS7

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: RM0083-8J52

Application*: WB

Rabbit Anti-LGALS7 Recombinant Antibody (CBLG1-3079) (CBMAB-G1127-LY)

SDS

Target: LGALS7

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBLG1-3079

Application*: IC/IF

Mouse Anti-LGALS7 Recombinant Antibody (15j87) (CBMAB-G6321-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: 15j87

Application*: E, IC, IH, WB

Mouse Anti-LGALS7 Recombinant Antibody (15j88) (CBMAB-G6322-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: 15j88

Application*: E, IC, IH, WB

Rat Anti-LGALS7 Recombinant Antibody (8J52) (CBMAB-G6323-LY)

SDS

Target: LGALS7

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: 8J52

Application*: IH, WB

Mouse Anti-LGALS7 Recombinant Antibody (MM0301-3Z10) (CBMAB-G6324-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: MM0301-3Z10

Application*: WB

Mouse Anti-LGALS7 Recombinant Antibody (CBLG1-2373) (CBMAB-G6325-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBLG1-2373

Application*: IC, C/P, E (IA), WB

Mouse Anti-LGALS7 Recombinant Antibody (CBLG1-2374) (CBMAB-G6326-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBLG1-2374

Application*: IC, C/P, E (IA), WB

Mouse Anti-LGALS7 Recombinant Antibody (CBYJL-1531) (CBMAB-L1301-YJ)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJL-1531

Application*: E, WB

Mouse Anti-LGALS7 Recombinant Antibody (CBYCL-272) (CBMAB-L0173-YC)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYCL-272

Application*: WB, IC, P, C, E

Mouse Anti-LGALS7 Recombinant Antibody (CBYCL-273) (CBMAB-L0174-YC)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBYCL-273

Application*: WB, IC, P, C, E

Mouse Anti-LGALS7 Recombinant Antibody (CBYCL-274) (CBMAB-L0175-YC)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBYCL-274

Application*: E, WB

Mouse Anti-LGALS7 Recombinant Antibody (CBYCL-275) (CBMAB-L0176-YC)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYCL-275

Application*: E, WB

Mouse Anti-LGALS7 Recombinant Antibody (6B5) (CBMAB-A4941-LY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 6B5

Application*: WB, E

Mouse Anti-LGALS7 Recombinant Antibody (CBFYH-2629) (CBMAB-H0059-FY)

SDS

Target: LGALS7

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2629

Application*: F

Rat Anti-Lgals7 Recombinant Antibody (CBYJL-2411) (CBMAB-L2735-YJ)

SDS

Target: Lgals7

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBYJL-2411

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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