Rat Anti-LGALS7 Recombinant Antibody (RM0083-8J52) (CBMAB-G6320-LY)

Name: Rat Anti-LGALS7 Recombinant Antibody (RM0083-8J52)
SKU: CBMAB-G6320-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

RM0083-8J52

Application

Immunogen

Mouse recombinant Galectin-7

Specificity

Mouse

Antibody Isotype

IgG2

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

lectin, galactoside-binding, soluble, 7

Introduction

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19.

Entrez Gene ID

16858

UniProt ID

O54974

Alternative Names

Galectin-7; Pig1

Function

Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Biological Process

Apoptotic processIEA:UniProtKB-KW
Heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of CD4-positive, alpha-beta T cell proliferationManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of interferon-gamma productionManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of gene expressionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Nucleus
Secreted
May be secreted by a non-classical secretory pathway.

Wang, M. D., Tian, J., Zhang, J. H., Zhao, S. Y., Song, M. J., & Wang, Z. X. (2022). Human Galectin-7 Gene LGALS7 Promoter Sequence Polymorphisms and Risk of Spontaneous Intracerebral Hemorrhage: A Prospective Study. Frontiers in Molecular Neuroscience, 15, 840340.Wang, M. D., Tian, J., Zhang, J. H., Zhao, S. Y., Song, M. J., & Wang, Z. X. (2022). Human Galectin-7 Gene LGALS7 Promoter Sequence Polymorphisms and Risk of Spontaneous Intracerebral Hemorrhage: A Prospective Study. Frontiers in Molecular Neuroscience, 15, 840340.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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