Mouse Anti-RXFP1 Recombinant Antibody (3E3) (CBMAB-A4946-LY)

Name: Mouse Anti-RXFP1 Recombinant Antibody (3E3)
SKU: CBMAB-A4946-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3E3

Application

WB, ELISA

Immunogen

LGR7 (NP_067647, 68 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Relaxin/Insulin Like Family Peptide Receptor 1

Entrez Gene ID

59350

UniProt ID

Q9HBX9

Alternative Names

LGR7; LGR7.1; LGR7.10; LGR7.2; MGC138347; MGC142177; RXFPR1

Function

Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Biological Process

Biological Process activation of adenylate cyclase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process extracellular matrix organizationIEA:Ensembl
Biological Process hormone-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process lung connective tissue developmentIEA:Ensembl
Biological Process myofibroblast differentiationIEA:Ensembl
Biological Process nipple morphogenesisIEA:Ensembl
Biological Process parturitionIEA:Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 1-409
Helical: 410-430
Cytoplasmic: 431-443
Helical: 444-464
Extracellular: 465-486
Helical: 487-507
Cytoplasmic: 508-527
Helical: 528-548
Extracellular: 549-577
Helical: 578-598
Cytoplasmic: 599-629
Helical: 630-650
Extracellular: 651
Helical: 652-672
Cytoplasmic: 673-757

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

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Mouse Anti-RXFP1 Recombinant Antibody (CBYJL-150) (CAT#: CBMAB-L0221-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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