Mouse Anti-LHX1 Recombinant Antibody (4D1) (CBMAB-L1456-YJ)

Mouse

Human

4D1

IgG2a, κ

ELISA, IF, IHC

Partial recombinant corresponding to aa 1-100 from LHX1 (NP_005559) with GST tag. MW of the GST tag alone is 26kD.

Human

IgG2a, κ

Monoclonal

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

PBS, pH 7.2

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

aa 1-100

LHX1

LHX1 is a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. LHX1 is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. Diseases associated with LHX1 include Chromosome 17Q12 Deletion Syndrome and Mayer-Rokitansky-Kuster-Hauser Syndrome. Among its related pathways are Ectoderm Differentiation and Neural Crest Differentiation. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription corepressor activity. An important paralog of this gene is LHX5. It is a potential transcription factor. LHX1 may play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.

LIM1; LIM-1

Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.

Anatomical structure formation involved in morphogenesisISS:UniProtKB
Anatomical structure morphogenesisISS:UniProtKB
Animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Anterior/posterior axis specificationISS:UniProtKB
Anterior/posterior pattern specificationISS:UniProtKB
Branching involved in ureteric bud morphogenesisIEA:Ensembl
Cell-cell signalingISS:UniProtKB
Cellular response to fibroblast growth factor stimulusIEA:Ensembl
Cerebellar Purkinje cell differentiationISS:UniProtKB
Cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferationISS:UniProtKB
Cerebellum developmentISS:UniProtKB
Cervix developmentISS:UniProtKB
Comma-shaped body morphogenesisISS:UniProtKB
Dorsal spinal cord interneuron posterior axon guidanceISS:UniProtKB
Dorsal/ventral pattern formationISS:UniProtKB
Ectoderm formationISS:UniProtKB
Embryonic pattern specificationISS:UniProtKB
Embryonic retina morphogenesis in camera-type eyeISS:UniProtKB
Embryonic viscerocranium morphogenesisISS:UniProtKB
Endoderm formationISS:UniProtKB
Epithelium developmentISS:UniProtKB
Forebrain regionalizationISS:UniProtKB
Gastrulation with mouth forming secondISS:UniProtKB
Head developmentISS:UniProtKB
Horizontal cell localizationIEA:Ensembl
Kidney developmentISS:UniProtKB
Lateral motor column neuron migrationISS:UniProtKB
Mesendoderm developmentIEA:Ensembl
Mesonephric duct developmentIEA:Ensembl
Metanephric comma-shaped body morphogenesisIEA:Ensembl
Metanephric glomerulus developmentIEA:Ensembl
Metanephric part of ureteric bud developmentIEA:Ensembl
Metanephric renal vesicle morphogenesisIEA:Ensembl
Metanephric S-shaped body morphogenesisIEA:Ensembl
Motor neuron axon guidanceISS:UniProtKB
Negative regulation of transcription, DNA-templatedISS:UniProtKB
Nephric duct elongationIEA:Ensembl
Nephric duct morphogenesisISS:UniProtKB
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Oviduct developmentISS:UniProtKB
Oviduct epithelium developmentISS:UniProtKB
Paramesonephric duct developmentISS:UniProtKB
Pattern specification processISS:UniProtKB
Positive regulation of anterior head developmentISS:UniProtKB
Positive regulation of branching involved in ureteric bud morphogenesisISS:UniProtKB
Positive regulation of embryonic developmentISS:UniProtKB
Positive regulation of gastrulationISS:UniProtKB
Positive regulation of nephron tubule epithelial cell differentiationISS:UniProtKB
Positive regulation of transcription, DNA-templatedISS:UniProtKB
Post-embryonic developmentISS:UniProtKB
Primitive streak formationISS:UniProtKB
Pronephros developmentIEA:Ensembl
Regulation of gene expressionISS:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Renal vesicle morphogenesisISS:UniProtKB
Retina layer formationISS:UniProtKB
S-shaped body morphogenesisISS:UniProtKB
Somite rostral/caudal axis specificationIEA:Ensembl
Spinal cord association neuron differentiationISS:UniProtKB
Telencephalon developmentIEA:Ensembl
Transcription by RNA polymerase IIISS:UniProtKB
Ureter morphogenesisIEA:Ensembl
Ureteric bud developmentISS:UniProtKB
Urogenital system developmentISS:UniProtKB
Uterine epithelium developmentISS:UniProtKB
Uterus developmentISS:UniProtKB
Vagina developmentISS:UniProtKB
Ventral spinal cord developmentIEA:Ensembl

Nucleus