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Mouse Anti-LIPH Recombinant Antibody (CBYJL-1789) (CBMAB-L1721-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Lipase H (LIPH). The antibody can be used for immunoassay techniques, such as ELISA, IF, IHC, WB.
See all LIPH antibodies

Summary

Host Animal
Mouse
Specificity
Human, Pig
Clone
CBYJL-1789
Antibody Isotype
IgG2a
Application
ELISA, IF, IHC, WB

Basic Information

Specificity
Human, Pig
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
LIPH
Introduction
LIPH is a membrane-bound member of the mammalian triglyceride lipase family. LIPH catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility.
Entrez Gene ID
Human200879
Pig100737989
UniProt ID
HumanQ8WWY8
PigF1SFK2
Alternative Names
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Function
Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
Biological Process
Fatty acid biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Lipid catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Phosphatidic acid biosynthetic processTAS:Reactome
Triglyceride catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
Cell membrane
Involvement in disease
Hypotrichosis 7 (HYPT7):
A condition characterized by the presence of less than the normal amount of hair. Affected individuals have sparse or absent scalp, axillary and body hair and sparse eyebrows and eyelashes. HYPT7 inheritance is autosomal recessive.
Woolly hair autosomal recessive 2 (ARWH2):
A hair shaft disorder characterized by fine and tightly curled hair. Compared to normal curly hair that is observed in some populations, woolly hair grows slowly and stops growing after a few inches. Under light microscopy, woolly hair shows some structural anomalies, including trichorrhexis nodosa and tapered ends. Some individuals may present with hypotrichosis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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