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Mouse Anti-LMO3 Recombinant Antibody (CBYJL-1878) (CBMAB-L1875-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Lim Domain Only 3 (LMO3). The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all LMO3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-1878
Antibody Isotype
IgG2b, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
LMO3 (NP_061110, 91 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MRAKDNVYHL DCFACQLCNQ RFCVGDKFFL KNNMILCQTD YEEGLMKEGY APQVR.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 91-145

Target

Full Name
LIM domain only 3 (rhombotin-like 2)
Introduction
LMO3 belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to function in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been described for this gene.
Entrez Gene ID
UniProt ID
Alternative Names
RBTN3; RHOM3; RBTNL2; Rhom-3
Biological Process
Negative regulation of ERK1 and ERK2 cascadeManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of fat cell differentiationManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of glucocorticoid receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of peroxisome proliferator activated receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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