Rat Anti-Ly6c1 Recombinant Antibody (CBYCL-561) (CBMAB-L0462-YC)

Name: Rat Anti-Ly6c1 Recombinant Antibody (CBYCL-561)
SKU: CBMAB-L0462-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

CBYCL-561

Application

FC, IP, WB

Immunogen

Murine Ly-6C (T-cell activating)

Specificity

Mouse

Antibody Isotype

IgG2c

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Lymphocyte Antigen 6 Complex, Locus C1

Introduction

LY6C is a member of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by aglycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction.

Entrez Gene ID

17067

UniProt ID

P0CW02

Alternative Names

AA959465; AA682074; Ly6c; Ly-6C; Ly-6C1

Biological Process

Acetylcholine receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Shay, T. F., Sullivan, E. E., Ding, X., Chen, X., Ravindra Kumar, S., Goertsen, D., ... & Gradinaru, V. (2023). Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Science Advances, 9(16), eadg6618.

Morimoto, J., Matsumoto, M., Miyazawa, R., Oya, T., Tsuneyama, K., & Matsumoto, M. (2022). No major impact of two homologous proteins Ly6C1 and Ly6C2 on immune homeostasis. ImmunoHorizons, 6(3), 202-210.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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