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Mouse Anti-LY86 Recombinant Antibody (CBYJL-2216) (CBMAB-L2455-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Lymphocyte Antigen 86 (LY86). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all LY86 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-2216
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
LY86 (AAH38846, 26 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: AWPTHVVCSD SGLEVLYQSC DPLQDFGFSV EKCSKQLKSN INIRFGIILR EDIKELFLDL ALMSQGSSVL NFSYPICEAALPKFSFCGRR KGEQIYYAGP.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 26-125

Target

Full Name
lymphocyte antigen 86
Introduction
Diseases associated with LY86 include Muscular Dystrophy, Duchenne Type and Parametritis. Among its related pathways are Activated TLR4 signalling and Innate Immune System.
Entrez Gene ID
9450
UniProt ID
O95711
Alternative Names
MD1; MD-1; MMD-1; dJ80N2.1; lymphocyte antigen 86; MD-1, RP105-associated; ly-86; protein MD-1
Function
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
Biological Process
Inflammatory responseIEA:UniProtKB-KW
Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of lipopolysaccharide-mediated signaling pathwayManual Assertion Based On ExperimentIGI:MGI
Cellular Location
Secreted, extracellular space
Associated with CD180 at the cell surface.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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