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Rat Anti-LY86 (AA 20-162) Recombinant Antibody (CBFYM-1233) (CBMAB-M1390-FY)

This product is rat antibody that recognizes LY86. The antibody CBFYM-1233 can be used for immunoassay techniques such as: WB.
See all LY86 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYM-1233
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse MD-1, Asp20-Ser162
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 20-162

Target

Full Name
lymphocyte antigen 86
Introduction
DNA Methylation of the LY86 Gene is Associated With Obesity, Insulin Resistance, and Inflammation.
Entrez Gene ID
17084
UniProt ID
O88188
Alternative Names
MD1; MD-1; ly86_tv2
Function
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
Biological Process
Inflammatory responseIEA:UniProtKB-KW
Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of lipopolysaccharide-mediated signaling pathwayManual Assertion Based On ExperimentIGI:MGI
Cellular Location
Secreted, extracellular space
Associated with CD180 at the cell surface.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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