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Rat Anti-Ly86 Recombinant Antibody (CBYJL-2482) (CBMAB-L2865-YJ)

Provided herein is a Rat monoclonal antibody, which binds to Lymphocyte Antigen 86 (Ly86). The antibody can be used for immunoassay techniques, such as FC.
See all Ly86 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJL-2482
Antibody Isotype
IgG2a, κ
Application
FC

Basic Information

Immunogen
Mouse RP105/MD-1 transfected NRK cells.
Specificity
Mouse
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
lymphocyte antigen 86
Introduction
Ly86 may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Ly86 is important for efficient CD180 cell surface expression.
Entrez Gene ID
17084
UniProt ID
O88188
Alternative Names
MD1; MD-1; ly86_tv2; lymphocyte antigen 86; ly-86; protein MD-1
Function
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
Biological Process
Inflammatory responseIEA:UniProtKB-KW
Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of lipopolysaccharide-mediated signaling pathwayManual Assertion Based On ExperimentIGI:MGI
Cellular Location
Secreted, extracellular space
Associated with CD180 at the cell surface.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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