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Mouse Anti-LY86 (AA 26-125) Recombinant Antibody (CBFYM-1232) (CBMAB-M1389-FY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBFYM-1232
Antibody Isotype
IgG2a, k
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa26-125 from LY86 (AAH38846) with GST tag. MW of the GST tag alone is 26kD.
Specificity
Human, Mouse
Antibody Isotype
IgG2a, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 26-125

Target

Full Name
lymphocyte antigen 86
Introduction
DNA Methylation of the LY86 Gene is Associated With Obesity, Insulin Resistance, and Inflammation.
Entrez Gene ID
Human9450
Mouse17084
UniProt ID
HumanO95711
MouseO88188
Alternative Names
MD1; MD-1; MMD-1; dJ80N2.1
Function
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
Biological Process
Inflammatory responseIEA:UniProtKB-KW
Innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of lipopolysaccharide-mediated signaling pathwayManual Assertion Based On ExperimentIGI:MGI
Cellular Location
Secreted, extracellular space
Associated with CD180 at the cell surface.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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