Mouse Anti-MAATS1 (AA 1-313) Recombinant Antibody (CBFYM-1245) (CBMAB-M1404-FY)

Name: Mouse Anti-MAATS1 (AA 1-313) Recombinant Antibody (CBFYM-1245)
SKU: CBMAB-M1404-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYM-1245

Application

IHC-P, WB

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-313

More Infomation

Target

Full Name

MYCBP Associated And Testis Expressed 1

Introduction

MAATS1 is a Protein Coding gene. Gene Ontology annotations related to this gene include adenosylmethionine decarboxylase activity.

Entrez Gene ID

89876

UniProt ID

Q7Z4T9

Alternative Names

MYCBP Associated And Testis Expressed 1; AMY-1-Associating Protein Expressed In Testis 1; MYCBP/AMY-1-Associated Testis-Expressed Protein 1; MYCBP/AMY-1-Associated, Testis Expressed 1; MYCBP-Associated, Testis Expressed 1; Spermatogenesis Associated 26; MYCBP-Binding Protein; Protein MAATS1; C3orf15; CFAP91

Function

Involved in sperm flagellum axonemal organization and function (PubMed:12223483, PubMed:32161152).
May regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).

Biological Process

Axonemal central apparatus assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Cilium movementISS:UniProtKB
SpermatogenesisManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Mitochondrion
Cytoplasm
Cytoplasm, cytoskeleton, cilium axoneme
Localized in the neck of the sperm.
Isoform 7:
Cytoplasm

Involvement in disease

Spermatogenic failure 51 (SPGF51):
An autosomal recessive infertility disorder characterized by asthenoteratozoospermia. Spermatozoa exhibit multiple morphologic abnormalities, including absent, short, bent, coiled and irregular-caliber flagella. Abnormalities of the sperm head, base, and acrosome have also been observed.

PTM

Phosphorylated by PKA.

Martinez, G., Beurois, J., Dacheux, D., Cazin, C., Bidart, M., Kherraf, Z. E., ... & Coutton, C. (2020). Biallelic variants in MAATS1 encoding CFAP91, a calmodulin-associated and spoke-associated complex protein, cause severe astheno-teratozoospermia and male infertility. Journal of medical genetics, 57(10), 708-716.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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