Mouse Anti-MAATS1 Recombinant Antibody (CBYY-C0814) (CBMAB-C2250-YY)

Name: Mouse Anti-MAATS1 Recombinant Antibody (CBYY-C0814)
SKU: CBMAB-C2250-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-C0814

Application

WB, IHC, IHC-P

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-313 of human C3orf15 (NP_203528) produced in E.coli

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Affinity purified

Concentration

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

MYCBP Associated And Testis Expressed 1

Entrez Gene ID

89876

UniProt ID

Q7Z4T9

Alternative Names

AAT1; CFAP91; C3orf15; CaM-IP2; SPATA26; AAT1alpha

Function

Involved in sperm flagellum axonemal organization and function (PubMed:12223483, PubMed:32161152).
May regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).

Biological Process

Axonemal central apparatus assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Cilium movementISS:UniProtKB
SpermatogenesisManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Mitochondrion
Cytoplasm
Cytoplasm, cytoskeleton, cilium axoneme
Localized in the neck of the sperm.
Isoform 7:
Cytoplasm

Involvement in disease

Spermatogenic failure 51 (SPGF51):
An autosomal recessive infertility disorder characterized by asthenoteratozoospermia. Spermatozoa exhibit multiple morphologic abnormalities, including absent, short, bent, coiled and irregular-caliber flagella. Abnormalities of the sperm head, base, and acrosome have also been observed.

PTM

Phosphorylated by PKA.

Martinez, G., Beurois, J., Dacheux, D., Cazin, C., Bidart, M., Kherraf, Z. E., ... & Coutton, C. (2020). Biallelic variants in MAATS1 encoding CFAP91, a calmodulin-associated and spoke-associated complex protein, cause severe astheno-teratozoospermia and male infertility. Journal of medical genetics, 57(10), 708-716.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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