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Mouse Anti-MAP3K21 Recombinant Antibody (CBFYM-1524) (CBMAB-M1687-FY)

This product is mouse antibody that recognizes MAP3K21. The antibody CBFYM-1524 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all MAP3K21 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBFYM-1524
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 21
Introduction
MAP3K21 is a Protein Coding gene. An important paralog of this gene is MAP3K9.
Entrez Gene ID
Human84451
Mouse234878
Rat307950
UniProt ID
HumanQ5TCX8
MouseQ8VDG6
RatD4A454
Alternative Names
Mitogen-Activated Protein Kinase Kinase Kinase 21; Mixed Lineage Kinase 4; Mitogen-Activated Protein Kinase Kinase Kinase MLK4; EC 2.7.11.25; MLK4; DJ862P8.3; EC 2.7.11; KIAA1804
Function
Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
Biological Process
Protein autophosphorylationISS:UniProtKB
Protein phosphorylationISS:UniProtKB
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
PTM
Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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