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Mouse Anti-MAST2 Recombinant Antibody (3F9) (CBMAB-A5312-LY)

The product is antibody recognizes MAST2. The antibody 3F9 immunoassay techniques such as: WB, ELISA.
See all MAST2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3F9
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
MAST2 (AAH15816, 688 a.a. ~ 792 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
microtubule associated serine/threonine kinase 2
Entrez Gene ID
23139
UniProt ID
Q6P0Q8
Alternative Names
FLJ39200; KIAA0807; MAST205; MTSSK; RP4-533D7.1
Function
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).
Biological Process
Cytoskeleton organization Source: GO_Central
Intracellular signal transduction Source: GO_Central
Peptidyl-serine phosphorylation Source: GO_Central
Protein phosphorylation Source: UniProtKB
Regulation of interleukin-12 production Source: UniProtKB
Spermatid differentiation Source: UniProtKB
Cellular Location
Cytoskeleton
Plasma membrane
Cell membrane
Note: Recruited to the sub-membranous area on interaction with CDHR2.
PTM
Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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